The National Center for Health Statistics (NCHS) at the Centers for Disease Control and Prevention collects information on deaths involving drugs commonly associated with fatal overdose. This information is available in a searchable database called CDC Wonder. The NCHS also provides 12-month-ending Provisional Drug Overdose Death Counts by state and drug category.
The CDC also provides timely data related to unintentional and undetermined intent drug overdose deaths by participating jurisdiction through the State Unintentional Drug Overdose Reporting System (SUDORS). Similar data related to nonfatal drug overdoses are reported through CDC’s Drug Overdose Surveillance and Epidemiology (DOSE) system.
Figure 1. National Drug-Involved Overdose Deaths—Number Among All Ages, United States, 1999–2024. More than 79,000 persons in the United States died from drug-involved overdose in 2024, including deaths involving illicit drugs and prescription opioids. After increasing to more than 107,000 deaths in 2022 and remaining above 105,000 deaths in 2023, the number of overdose deaths declined to 79,384 in 2024. Source: CDC National Center for Health Statistics, National Vital Statistics System (NVSS) mortality data.